Medicinal Chemistry

Medicinal Chemistry from Cardiff University, is a research area within which you can focus your studies as part of our suite of Pharmacy and Pharmaceutical Sciences research programmes (MPhil, MD, PhD).

Medicinal Chemistry from Cardiff University aim is to offer knowledge and expertise for a career in the pharmaceutical industry, academia or in primary/secondary care.

Distinctive features

• The work involves close collaboration with virologists and biochemists throughout Europe, and USA.

• The School of Pharmacy and Pharmaceutical Sciences has excellent facilities for the group. It has purchased a Bruker 500MHz NMR spectrometer, a Fisons Platform II Mass Spectrometer (set up for electrospray and APCI) and several Silicon Graphics workstations and extensive software including Sybyl, Macromodel, DOCK, GRID and Oxford Molecular Software. The synthetic chemistry laboratories have recently been refurbished and each researcher has their own fume hood.

• There are excellent library facilities and computer links from all the laboratories allowing access to a wide range of databases.

Research themes

• Molecular modelling

• Nucleotide prodrugs (“Protides”) especially as anticancer and antiviral agents

• This research group enjoys well-equipped laboratories.

There is close collaboration with virologists and biochemists throughout Europe, and USA.

Area of expertise

• Computer-based molecular graphics

• synthesis and analysis of bioactive molecules

• applying a wide variety of spectroscopic and other analytical methods.