Organic Synthesis

The School of Chemistry has developed a particular strength in Organic Synthesis, with a research group dedicated to this exciting area of study. As part of the Chemistry (PhD/MPhil) programme, students can conduct their research within this Organic Synthesis group, at Cardiff University.

Key Facts

The research carried out within the Organic Synthesis group from Cardiff University , is largely focused on the development of novel synthetic methods and applications of these in target synthesis, most often either natural products or biologically active compounds of pharmaceutical or agrochemical significance. In many cases, the inspiration for developing the new methodology arises from a consideration of the structural features of such targets.

A particularly strong theme is the formation of such compounds by the electrophile-driven addition of nucleophiles to unsaturated carbon-carbon bonds. A long standing interest in pericyclic reactions continues in the areas of Diels-Alder chemistry, various sigmatropic rearrangements and electrocyclic reactions.

Organocatalysis, an increasingly important area in view of the toxicity of many transition metals, is well represented within the group. Current target types include complex polycyclic peptides, alkaloids, steroids, terpene alkaloids and plant-derived oxygen heterocycles.

Curriculum structure:

• Eachyear the School of Chemistry welcomes applicants who have secured funding fromexternal sponsors, or who are self-funded.

• We have an extensive list of projects that are available. Details for each project can be obtained bycontacting the member of academic staff directly.Please state which project(s) you would like to be considered for on your application form.
• In the first instance, you should submit aCV & Covering Letter to the project supervisor detailing which projects you would like to be considered for.