Pharmacology and Physiology

Pharmacology and Physiology from Cardiff University, is a research area within which you can focus your studies as part of our suite of Pharmacy and Pharmaceutical Sciences research programmes (MPhil, MD, PhD).

Research study in the Pharmacology and Physiology area, at Cardiff University ,involves understanding of physiological regulation and disease processes, identifying and validating novel drug targets, mechanisms of drug action.

Areas of Expertise

Expertise includes elucidating mechanisms of drug action at all levels of organisation, from intracellular sites, membranes and cells through to tissues, organs and intact organisms.

Specific methodologies include:

• In vivo and in vitro cardiovascular and pulmonary pharmacology,
• Cancer therapeutics and neurogenerative diseases,
• Enzyme purification,
• Spectral analysis,
• Immunoassay,
• Radioligand binding,
• In situ hybridisation,
• PCR,
• cDNA analysis,
• Western analysis and immunoprecipitation,
• Proteome mapping,
• Receptor cloning,
• Cell culture,
• Single cell electrophysiology,
• Live cell imaging,
• Bioluminescence,
• Immunocytochemistry of total and activated proteins and behavioural testing.

Research themes

• Cell signalling, especially in cancer and cardiovascular disease
• Airway diseases
• Smooth muscle pharmacology
• Neurodegenerative diseases
• Applications of chemo/bioluminescence