PhD student Schwann Cell Biology in Health & Disease

BackgroundThe faculty of medicine and life sciences contributes to sustainable solutions for health-related issues as part of the civic Hasselt University. The faculty focuses on excellence in education and research and connects with society through a strong collaboration with our partners. Starting from continuous attention for quality and innovation, the faculty is a breeding ground and magnet for talent with an open view on society, from the region to the world. The Biomedical Research Institute (BIOMED) of Hasselt University conducts high level multidisciplinary research to advance progress in human life sciences. High-end technology is used to deliver novel insights in three main disease areas: (neuro)immunology, neuroscience and cardiovascular disease. BIOMED aims to translate new scientific discoveries into applications that contribute to a healthy society in line with the civic ambition of Hasselt University. This project is funded by FWO and is a collaboration between Prof. Dr. Niels Hellings (NIC&R lab) and Prof. Dr. Esther Wolfs (FIERCE lab), integrating expertise in de- and remyelination, Schwann cell biology, and Charcot-Marie-Tooth Disease type 1A (CMT1A). Within this stimulating environment, we are looking for a highly motivated PhD student. The project investigates the involvement of a novel factor in peripheral nerve myelination as well as its therapeutic potential for peripheral neuropathies, with a focus on CMT1A.
Job contentYou will prepare a PhD on a project that focuses on a novel factor that drives peripheral nerve myelination with a specific focus on Schwann cell biology. In addition to the fundamental aspects of this topic, you will evaluate the therapeutic potential of this factor in the context of peripheral demyelinating diseases, with a particular focus on Charcot-Marie-Tooth disease type 1A, the most prevalent inherited peripheral neuropathy causing demyelination. To this end, we offer you:
– A challenging project in two different research groups  in BIOMED (NIC&R and FIERCE labs), in a dynamic and stimulating working environment for high-level neuroscience research
– The research will be performed at the molecular, cellular, and organismal level
– Use of rapidly advancing technologies in glial cell biology, induced pluripotent stem cell research and mouse models
– Access to state-of-the-art infrastructure and core facilities in a vibrant, excellent research environment
– Dedicated training programs available through UHasselt to broaden your expertise and enhance your skill set
– Participation in (inter)national conferences and (inter)national collaborations
Profile
– You have completed or are about to complete a Master in biomedical sciences, biotechnology, bio-engineering, biochemistry, biology, neurosciences, or an equivalent specialisation.Final-year students are (likewise) encouraged to apply.
– You achieved good academic results, and/or you can show relevant academic output (e.g. publications, mobility).
– You have a strong interest in fundamental and translational scientific research in the field of neuroscience.
– You have demonstrable experience (e.g. by internships) in executing biomedical research.
– Experience with primary cell cultures and animal models is an asset.
– You exhibit excellent communication skills, and you master the English language, both orally and in writing.
– You work in a goal-oriented and flexible way. You are able to efficiently plan your work, allowing you to achieve challenging, yet feasible goals, and you adjust your planning if necessary.
– You actively contribute to a positive working environment, yyou are a team player, and you enjoy making connections between different research groups.
– You must hold a FELASA C degree for handling small model organisms (or equivalent).
OfferYou will be appointed and paid as PhD student.We offer you an appointment for a period of 2 years that will be extended for another 2 years, after positive evaluation.

You are encouraged to apply for mandate specific funding
Selection procedureYou can only apply online up to and including 03 March 2025.The selection procedure consists of a preselection based on application file and an interview.
Further informationProf. dr. Niels HELLINGS, +32-11-269268, [email protected]. dr. Esther WOLFS, +32-11-269296, [email protected] questions about the selection procedure, please email [email protected].