Utility of in silico prediction tools to aid variant interpretation

ThisUtility of in silico prediction tools to aid variant interpretation project at University of Dundee will apply a variety of methods to assess whether these novel computational approaches can variant interpretation in the clinical genetic testing workflow.

This Utility of in silico prediction tools to aid variant interpretation project at University of Dundee deals with the fact that accurate variant interpretation is essential for the successful implementation of genetic testing in the clinical setting. Large-scale population-based sequencing projects have provided unprecedented insight into great spectrum of rare coding variation that occurs within the background population. Differentiating genuine disease associated pathogenic variants from rare neutral variants remains a major barrier to the wider implementation of genetic testing (i.e. population-level testing).

Student background

The student should have a background and interest in relevant areas (e.g. genetics, molecular biology, bioinformatics).

Course subjects

• To obtain additional information about the programme, we kindly suggest that you visit the programme website, where you can find further details and relevant resources.