Postdoctoral Scientist on Light-based 3D Printing of Articular Cartilage

Postdoctoral Scientist on Light-based 3D Printing of Articular Cartilage
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Articular cartilage injuries are widespread and can increase the risk of early onset osteoarthritis. The field of tissue engineering and bioprinting is constantly searching for new methods to create biomimetic tissue models which better replicate the organization of native tissues and promote their healing.  Here bioprinting strategies have the potential to revolutionize the functionality of tissues used in regenerative medicine.

The Tissue Engineering and Biofabrication Laboratory (Prof. Marcy Zenobi-Wong) within the Department of Health Sciences & Technolgy (D-HEST) at ETH Zürich in Zurich, Switzerland, uses bioprinting to produce tissues which address unmet clinical needs. The laboratory  has recently developed a light-based 3D printing technique, capable of creating architectural cues which guide cell alignment and extracellular matrix deposition.  Based on this technology, the next generation in situ printer will be developed to specifically treat articular cartilage injuries.

Project background
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You will join a large European network interested in improving clinical options for cartilage repair.  The goal of this project is to validate a light based printer for use directly in the operation room.  This new printer will be able to crosslink photoresins and cells directly into the patient’s cartilage defect, thereby promoting regeneration of the joint.

Job description
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Coordination of in vitro validation and modeling of printed cartilage
Coordination of pre-clinical testing of in situ printed cartilage
Oversight of regulatory and safety testing of device and contact with regulatory and standardization bodies
Contact with end-users stakeholders
Commercial exploitation of results
Project reporting and management
Interest in in silico modeling and machine learning approaches to predict scaffold potency (optional)

Profile
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You have a PhD in biomedical engineering, mechanical engineering, biology, material science or related fields. Previous experience with startups, product commercialization, CE marking, and regulatory affairs is advantageous. This project is embedded within a large European consortium, therefore a flair for excellent written and oral communciation as well as effective and charismatic managerial skills are essential.

We offer
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We offer you a stimulating, collaborative, cross-disciplinary environment in a world-class research institution. ETH Zürich is an outstanding employer with excellent compensation and benefits, with ample opportunities for career development and mentoring. We encourage experimentation and creativity by actively promoting the learning of new technologies and approaches on the job.
Working, teaching and research at ETH Zurich (https://ethz.ch/en/the-eth-zurich/working-teaching-and-research.html)

We value diversity
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In line with our values, ETH Zurich encourages an inclusive culture. We promote equality of opportunity, value diversity and nurture a working and learning environment in which the rights and dignity of all our staff and students are respected. Visit our Equal Opportunities and Diversity website to find out how we ensure a fair and open environment that allows everyone to grow and flourish.

Curious? So are we.
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Curious? We look forward to receiving your application!

Your online application includes the following documents:

CV and publication list
Description of research interests
Name and contact information of 3-4 references

The position is available from January 1, 2025.  Please note that we exclusively accept applications submitted through our online application portal. Applications via email or postal services will not be considered.

Further information about our Institute and Laboratory can be found on our website. Questions regarding the position should be directed to Prof. Marcy Zenobi-Wong, email: [email protected] (no applications).

About ETH Zürich
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ETH Zurich is one of the world’s leading universities specialising in
science and technology. We are renowned for our excellent education,
cutting-edge fundamental research and direct transfer of new knowledge
into society. Over 30,000 people from more than 120 countries find our
university to be a place that promotes independent thinking and an
environment that inspires excellence. Located in the heart of Europe,
yet forging connections all over the world, we work together to
develop solutions for the global challenges of today and tomorrow.