Gastroenterology

The Department of Cellular and Molecular Physiology builds on a long and prestigious history and remains a leading international centre for research into the fundamental principles of human physiology. The Gastroenterology program is offered by University of Liverpool.

Laboratory research is based mainly on the University campus in the Henry Wellcome Laboratory of Molecular & Cellular Gastroenterology . We also conduct clinical research and trials at the Royal Liverpool & Broadgreen University Hospital.

Key Features

• The focus of theGastroenterology program from University of Liverpool is on “translational” research: taking advances in basic medical research out of the laboratory and into the hospital clinic ‘from the bench to bedside’. This involves a whole range of experimental techniques, from mechanistic studies involving cell-lines through to patient studies and clinical trials.

Facilities

• The research infrastructure of the Institute of Translational Medicine is designed to give researchers access to world class facilities in the best possible environment.
• The centres, facilities and resources give us the ability to drive biomedical research from patient samples to the laboratory bench and vice versa from newly generated drug compounds into clinical trials. They provide powerful, productive collaborations between experts within the University and organisations worldwide.

Our research areas specifically focus on:

• Gastrointestinal (GI) Cancers - molecular pathogenesis; regulation of apoptosis in the GI tract; the gastrin family of peptides; epithelial glycobiology; development of biomarkers

• Inflammatory Bowel Disease (IBD) – role of immune cells; bacterial factors; the development and assessment of novel therapies

• Gastric physiology and response to NSAIDs

• Gut microbiota, enteric infection and bacteraemia

• Volatile Organic Compounds in GI disease

• Development and imaging of 3-D ‘mini-gut’ models.